Informationen über Pharmazie
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Raman spectroscopy fulfils a critical analytical role at many stages of the pharmaceutical product design and production process. Applications range from monitoring and controlling large scale manufacturing processes, to profiling the distribution of active pharmaceutical ingredients (API) and excipients at different stages in a formulation cycle. Raman offers unparalleled polymorph discrimination, is capable of studying aqueous and solid samples, and is particularly suited to combining with other analytical techniques given that it provides non-destructive analysis requiring little or no sample preparation. This application note demonstrates how Renishaw's NExT filter accessory and inVia Raman microscope can be applied to directlyrecord polymorphic lattice information. The polymorphic discriminatory power is illustrated using different carbamazepine polymorphs as a real case example, where complex data interpretation is not required for unequivocal differentiation. This application note illustrates how Renishaw's inVia Raman microscope can help the pharmaceutical industry with high throughput screening (HTS), formulation, and pharmaceutical identification and characterisation.
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